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Current strategies in cancer gene therapy  • REVIEW ARTICLE Anas El-Aneed SummaryPlus | Full Text + Links | PDF (320 K) | |||
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Antiangiogenic versus cytotoxic therapeutic approaches to human pancreas cancer: an experimental study with a vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor and gemcitabine  • ARTICLE Guido Bocci, Romano Danesi, Gabriele Marangoni, Anna Fioravanti, Ugo Boggi, Irene Esposito, Alessandro Fasciani, Elena Boschi, Daniela Campani, Generoso Bevilacqua et al. SummaryPlus | Full Text + Links | PDF (577 K) | |||
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Inhibition of UVA irradiation-modulated signaling pathways by rutaecarpine, a quinazolinocarboline alkaloid, in human keratinocytes  • ARTICLE Sung-Mok Beak, Seung-Hwan Paek, Yurngdong Jahng, Yong Soo Lee and Jung-Ae Kim SummaryPlus | Full Text + Links | PDF (516 K) | |||
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Ghrelin and des-acyl ghrelin both inhibit isoproterenol-induced lipolysis in rat adipocytes via a non-type 1a growth hormone secretagogue receptor  • ARTICLE Giampiero Muccioli, Nicoletta Pons, Corrado Ghè, Filomena Catapano, Riccarda Granata and Ezio Ghigo SummaryPlus | Full Text + Links | PDF (198 K) | |||
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Sensitization of vanilloid receptor 1 induced by bradykinin via the activation of second messenger signaling cascades in rat primary afferent neurons  • ARTICLE He-Bin Tang, Atsuko Inoue, Kyoko Oshita and Yoshihiro Nakata SummaryPlus | Full Text + Links | PDF (492 K) | |||
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Andrographolide acts through inhibition of ERK1/2 and Akt phosphorylation to suppress chemotactic migration  • ARTICLE Hwei-Ru Tsai, Li-Ming Yang, Wei-Jern Tsai and Wen-Fei Chiou SummaryPlus | Full Text + Links | PDF (414 K) | |||
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κ-Opioid receptor stimulation inhibits growth of neonatal rat ventricular myocytes  • ARTICLE Guijun Wang, Hongxin Wang, Yanling Yang and Tak Ming Wong SummaryPlus | Full Text + Links | PDF (416 K) | |||
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Regulation of serotonin 5-HT2C receptors by chronic ligand exposure  • ARTICLE Mark G. Devlin, Nicola J. Smith, Olivia M. Ryan, Elizabeth Guida, Patrick M. Sexton and Arthur Christopoulos SummaryPlus | Full Text + Links | PDF (305 K) | |||
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Apoptotic activity of betulinic acid derivatives on murine melanoma B16 cell line  • ARTICLE Wing-Keung Liu, Joyce C.K. Ho, Florence W.K. Cheung, Bonnie P.L. Liu, Wen-Cai Ye and Chun-Tao Che SummaryPlus | Full Text + Links | PDF (550 K) | |||
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Inhibition by tranilast of nifedipine-induced proliferation of cultured human gingival fibroblasts  • SHORT COMMUNICATION Toshimi Hattori and Pao-Li Wang SummaryPlus | Full Text + Links | PDF (109 K) | |||
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Urantide mimics urotensin-II induced calcium release in cells expressing recombinant UT receptors  • SHORT COMMUNICATION Valeria Camarda, Wei Song, Erika Marzola, Martina Spagnol, Remo Guerrini, Severo Salvadori, Domenico Regoli, Jonathan P. Thompson, David J. Rowbotham, David J. Behm et al. SummaryPlus | Full Text + Links | PDF (155 K) | |||
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Opioid agonist and antagonist treatment differentially regulates immunoreactive μ-opioid receptors and dynamin-2 in vivo  • ARTICLE Byron C. Yoburn, Vishal Purohit, Kaushal Patel and Qiuyu Zhang SummaryPlus | Full Text + Links | PDF (357 K) | |||
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Dopamine D4 receptors inhibit depolarization-induced [3H]GABA release in the rat subthalamic nucleus  • ARTICLE Benjamín Floran, Leonor Floran, David Erlij and Jorge Aceves SummaryPlus | Full Text + Links | PDF (146 K) | |||
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Analgesic effect of TT-232, a heptapeptide somatostatin analogue, in acute pain models of the rat and the mouse and in streptozotocin-induced diabetic mechanical allodynia  • ARTICLE János Szolcsányi, Kata Bölcskei, Árpád Szabó, Erika Pintér, Gábor Pethő, Krisztián Elekes, Rita Börzsei, Róbert Almási, Tamás Szűts, György Kéri and Zsuzsanna Helyes SummaryPlus | Full Text + Links | PDF (222 K) | |||
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Effects of neurosteroids on ischemia–reperfusion injury in the rat retina: role of σ1 recognition sites  • SHORT COMMUNICATION Claudio Bucolo and Filippo Drago SummaryPlus | Full Text + Links | PDF (178 K) | |||
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Neuroprotective and neurotoxic effects of cyclosporine A on transient focal ischemia in mdr1a knockout mice  • SHORT COMMUNICATION Michihiro Murozono, Shohei Matsumoto, Eriko Matsumoto, Atsushi Isshiki and Yasuo Watanabe SummaryPlus | Full Text + Links | PDF (131 K) | |||
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Suppressing effect of the cannabinoid CB1 receptor antagonist, SR 141716, on alcohol's motivational properties in alcohol-preferring rats  • ARTICLE Giancarlo Colombo, Giovanni Vacca, Salvatore Serra, Mauro A.M. Carai and Gian Luigi Gessa SummaryPlus | Full Text + Links | PDF (129 K) | |||
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Within-session repeated acquisition behavior in rats as a potential model of executive function  • ARTICLE Harlan E. Shannon and Patrick L. Love SummaryPlus | Full Text + Links | PDF (620 K) | |||
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Effects of rolipram, a phosphodiesterase 4 inhibitor, in combination with imipramine on depressive behavior, CRE-binding activity and BDNF level in learned helplessness rats  • ARTICLE Tetsuji Itoh, Miwa Tokumura and Kohji Abe SummaryPlus | Full Text + Links | PDF (402 K) | |||
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Opioid and monoamine systems mediate the discriminative stimulus of tramadol in rats  • ARTICLE Małgorzata Filip, Karolina Wydra, Salim Yalcin Inan, Marta Dziedzicka-Wasylewska and Edmund Przegaliński SummaryPlus | Full Text + Links | PDF (341 K) | |||
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Anxiolytic-like effects of PHCCC, an allosteric modulator of mGlu4 receptors, in rats  • SHORT COMMUNICATION Katarzyna Stachowicz, Kinga Kłak, Aleksandra Kłodzińska, Ewa Chojnacka-Wojcik and Andrzej Pilc SummaryPlus | Full Text + Links | PDF (101 K) | |||
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Behavioral sensitization to the discriminative stimulus effects of methamphetamine in rats  • SHORT COMMUNICATION Tsutomu Suzuki, Yoshie Fukuoka, Tomohisa Mori, Mayumi Miyatake and Minoru Narita SummaryPlus | Full Text + Links | PDF (201 K) | |||
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Lys-[Leu8,des-Arg9]-bradykinin blocks lipopolysaccharide-induced SHR aorta hyperpolarization by inhibition of Ca++- and ATP-dependent K+ channels  • ARTICLE Nelson C. Farias, Teresa Feres, Antonio C.M. Paiva and Therezinha B. Paiva SummaryPlus | Full Text + Links | PDF (500 K) | |||
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Superiority of YM598 over atrasentan as a selective endothelin ETA receptor antagonist  • ARTICLE Hironori Yuyama, Yukiko Noguchi, Akira Fujimori, Masashi Ukai, Noriko Fujiyasu, Akiyoshi Ohtake, Shuichi Sato, Katsumi Sudoh, Masao Sasamata and Keiji Miyata SummaryPlus | Full Text + Links | PDF (370 K) | |||
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Restoration of middle cerebral artery thrombosis by novel glycoprotein IIb/IIIa antagonist FK419 in guinea pig  • ARTICLE Akira Moriguchi, Kayoko Mihara, Toshiaki Aoki, Masashi Maeda, Nobuteru Tojo, Nobuya Matsuoka and Seitaro Mutoh SummaryPlus | Full Text + Links | PDF (457 K) | |||
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Atorvastatin enhances sildenafil-induced vasodilation through nitric oxide-mediated mechanisms  • ARTICLE Michele M. Castro, Elen Rizzi, Ricardo R. Rascado, Sabrina Nagassaki, Lusiane M. Bendhack and Jose E. Tanus-Santos SummaryPlus | Full Text + Links | PDF (209 K) | |||
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Synergistic interaction of endogenous platelet-activating factor and vasopressin in generating angina in rats  • ARTICLE János Nemcsik, Krisztina Kordás, József Egresits, Ferenc László, Ferenc A. László, Imre Pávó and Éva Morschl SummaryPlus | Full Text + Links | PDF (253 K) | |||
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Differences in the vascular selectivity and tolerance between the NO donor/β-blocker PF9404C and nitroglycerin  • ARTICLE Ana Ruiz-Nuño, Arancha Rosado, Antonio G. García, Manuela G. López and Mercedes Villarroya SummaryPlus | Full Text + Links | PDF (217 K) | |||
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Upregulation of Rho-kinase (ROCK-2) expression and enhanced contraction to endothelin-1 in the mesenteric artery from lipopolysaccharide-treated rats  • ARTICLE Kansu Büyükafşar, Onur Arıkan, Mustafa Ark, Havva Kubat and Elif Özveren SummaryPlus | Full Text + Links | PDF (291 K) | |||
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Pharmacological characterisation of the thermogenic effect of bupropion  • ARTICLE Yong-Ling Liu, Ian P. Connoley, David J. Heal and Michael J. Stock SummaryPlus | Full Text + Links | PDF (343 K) | |||
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Interaction between adenosine and allergen or compound 48/80 on lung parenchymal strips from actively sensitized Brown Norway rats  • ARTICLE Cedric Wolber, François Baur and John R. Fozard SummaryPlus | Full Text + Links | PDF (314 K) | |||
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In vivo and in vitro study of the influence of the anticholinesterase drug galantamine on motor and evacuative functions of rat gastrointestinal tract  • ARTICLE Valentin I. Turiiski, Atanas D. Krustev, Vladimir N. Sirakov and Damianka P. Getova SummaryPlus | Full Text + Links | PDF (347 K) | |||
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Mechanisms underlying postjunctional synergism between responses of the vas deferens to noradrenaline and ATP  • ARTICLE Neil C.E. Smith and Geoffrey Burnstock SummaryPlus | Full Text + Links | PDF (440 K) | |||
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Opioid profiles of Cys2-containing enkephalin analogues  • ARTICLE Nevena Pencheva, Peter Milanov, Lubomir Vezenkov, Tamara Pajpanova and Emilia Naydenova SummaryPlus | Full Text + Links | PDF (278 K) | |||
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Effect of pioglitazone on endotoxin-induced decreases in hepatic drug-metabolizing enzyme activity and expression of CYP3A2 and CYP2C11  • ARTICLE Jun Ueyama, Kiyoyuki Kitaichi, Masayuki Nadai, Mitsunori Iwase, Nao Tomyo, Hiroaki Kanazawa, Ryujiro Suzuki, Kenji Takagi, Kenzo Takagi and Takaaki Hasegawa SummaryPlus | Full Text + Links | PDF (562 K) | |||
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Blood flow-dependent changes in intrarenal nitric oxide levels during anesthesia with halothane or sevoflurane  • ARTICLE Kazuhito Kusudo, Kaori Ishii, Matlubur Rahman,Yasuharu Aki, Akira Miyatake, Hiroaki Kosaka, Shoji Kimura, Tatsuhiko Komatsu, Masataka Yokoyama, Kiyoshi Morita et al. SummaryPlus | Full Text + Links | PDF (177 K) | |||
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Inhibition of cyclooxygenase-2, but not cyclooxygenase-1, reduces prostaglandin E2 secretion from diabetic rat retinas  • SHORT COMMUNICATION Surya P. Ayalasomayajula, Aniruddha C. Amrite and Uday B. Kompella SummaryPlus | Full Text + Links | PDF (166 K) | |||
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Inhibition of interleukin-1β reduces mouse lung inflammation induced by exposure to cigarette smoke  • ARTICLE Paulo Castro, Alexandre Legora-Machado, Larissa Cardilo-Reis, Samuel Valença, Luis Cristóvão Porto, Christoph Walker, Claudia Zuany-Amorim and Vera Lucia Gonçalves Koatz SummaryPlus | Full Text + Links | PDF (336 K) | |||
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Involvement of enhanced neurokinin NK3 receptor expression in the severe asthma guinea pig model  • ARTICLE Osamu Mukaiyama, Kiyoshi Morimoto, Emi Nosaka, Sakiko Takahashi and Makoto Yamashita SummaryPlus | Full Text + Links | PDF (389 K) | |||
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15d-prostaglandin J2 reduces multiple organ failure caused by wall-fragment of Gram-positive and Gram-negative bacteria  • ARTICLE Laura Dugo, Marika Collin, Salvatore Cuzzocrea and Christoph Thiemermann SummaryPlus | Full Text + Links | PDF (214 K) | |||
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Effects of benidipine, a dihydropyridine-Ca2+ channel blocker, on expression of cytokine-induced adhesion molecules and chemoattractants in human aortic endothelial cells  • ARTICLE Masahiro Matsubara and Kazuhide Hasegawa SummaryPlus | Full Text + Links | PDF (1060 K) | |||
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Protective role of NF-κB1 (p50) in experimental pneumococcal meningitis  • SHORT COMMUNICATION Stefan Kastenbauer, Uwe Koedel, Falk Weih, Löms Ziegler-Heitbrock and Hans-Walter Pfister SummaryPlus | Full Text + Links | PDF (96 K) | |||
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Milrinone efficiently potentiates insulin secretion induced by orally but not intravenously administered glucose in C57BL6J mice  • ARTICLE Eva Degerman, Vincent Manganiello, Jens J. Holst and Bo Ahrén SummaryPlus | Full Text + Links | PDF (243 K) | |||
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Carbamazepine enhances brain production of kynurenic acid in vitro  • SHORT COMMUNICATION Tomasz Kocki, Janusz Kocki, Marian Wielosz, Waldemar A. Turski and Ewa M. Urbanska SummaryPlus | Full Text + Links | PDF (115 K) | |||
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Author Index  • INDEX PDF (64 K) | |||
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Keyword Index  • INDEX PDF (93 K) | |||
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Editorial Board  • EDITORIAL BOARD PDF (11 K) | |||
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